Atorvastatin Impurities

• Atorvastatin - EP Impurity B
• 
• Impurity: Atorvastatin - EP Impurity B
• Chemical Name: (3S,5R)-7-[3-(phenylcarbamoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid calcium salt

• Atorvastatin - EP Impurity D
• 
• Impurity: Atorvastatin - EP Impurity D
• Chemical Name: 3-(4-Fluorobenzoyl)-2-isobutyryl-3-phenyl-oxirane-2-carboxylic acid phenylamide

• Atorvastatin-2-hydroxy impurity
• 
• Impurity: Atorvastatin-2-hydroxy impurity
• Chemical Name: (3R,5R)-7-(3-(2-hydroxyphenylcarbamoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoic acid

• Atorvastatin-4-hydroxy impurity
• 
• Impurity: Atorvastatin-4-hydroxy impurity
• Chemical Name: (3R,5R)-7-(3-(4-hydroxyphenylcarbamoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoic acid

• Atorvastatin - EP Impurity F
• 
• Impurity: Atorvastatin - EP Impurity F
• Chemical Name: (3R,5R)-7-{(3R,5R)-7-[2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanamido}-3,5-dihydroxyheptanoic acid calcium salt

• Atorvastatin-5-Oxo-impurity
• 
• Impurity: Atorvastatin-5-Oxo-impurity
• Chemical Name: Atorvastatin-5-Oxo-impurity

• Ep Impurity G(Ats-3-O-methyl)
• 
• Impurity: Ep Impurity G(Ats-3-O-methyl)
• Chemical Name: (3R,5R)-7-(3-(phenylcarbamoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl)-5-hydroxy-3-methoxyheptanoic acid calcium salt

• Atorvastatin - EP Impurity A
• 
• Impurity: Atorvastatin - EP Impurity A
• Chemical Name: (3R,5R)-7-[3-(Phenylcarbamoyl)-2-isopropyl-4,5-diphenyl-1Hpyrrol-1-yl]-3,5-dihydroxyheptanoic acid sodium salt

• Atorvastatin - EP Impurity E
• 
• Impurity: Atorvastatin - EP Impurity E
• Chemical Name: (3S,5S)-7-[3-(phenylcarbamoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid calcium salt

• Atorvastatin - EP Impurity C
• 
• Impurity: Atorvastatin - EP Impurity C
• Chemical Name: (3R,5R)-7-[3-(phenylcarbamoyl)-4,5-bis(4-fluorophenyl)-2-isopropyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid calcium salt

• Atorvastatin Acetonide impurity
• 
• Impurity: Atorvastatin Acetonide impurity
• Chemical Name: 2-((4R,6R)-6-(2-(3-(phenylcarbamoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic acid

• Atorvastatin Lactone impurity
• 
• Impurity: Atorvastatin Lactone impurity
• Chemical Name: 5-(4-Fluorophenyl)-1-{2-[(2R, 4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-2-isopropyl-N,4-diphenyl-1H-pyrrole-3-carboxamide

• ATS-L-1 impurity
• 
• Impurity: ATS-L-1 impurity
• Chemical Name: tert-butyl 2-((4R,6R)-6-(2-(3-(phenylcarbamoyl)-2-isopropyl-4,5-diphenyl-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate

• Methyl ester impurity
• 
• Impurity: Methyl ester impurity
• Chemical Name: (3R,5R)-methyl 7-(3-(phenylcarbamoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate

• Amide impurity
• 
• Impurity: Amide impurity
• Chemical Name: (3R,5R)-7-{(3R,5R)-7-[2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanamido}-3,5-dihydroxyheptanoic acid calcium salt

• Atorvastatin Related Compound A
• 
• Impurity: Atorvastatin Related Compound A
• Chemical Name: (Desfluoro impurity, or (3R,5R)-7-[3-(phenylcarbamoyl)-2-isopropyl-4,5-diphenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid calcium salt)

• Atorvastatin Related Compound B
• 
• Impurity: Atorvastatin Related Compound B
• Chemical Name: (3S,5R isomer, or (3S,5R)-7-[3-(phenylcarbamoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid calcium salt)

• Atorvastatin Related Compound C
• 
• Impurity: Atorvastatin Related Compound C
• Chemical Name: (Difluoro impurity, or (3R,5R)-7-[3-(phenylcarbamoyl)-4,5-bis(4-fluorophenyl)-2-isopropyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid calcium salt)

• Atorvastatin Related Compound D
• 
• Impurity: Atorvastatin Related Compound D
• Chemical Name: (Epoxide impurity, or 3-(4-Fluorobenzoyl)-2-isobutyryl-3-phenyl-oxirane-2-carboxylic acid phenylamide)

• Atorvastatin Related Compound E
• 
• Impurity: Atorvastatin Related Compound E
• Chemical Name: (3S, 5S enantiomer of Atorvastatin Calcium)

• Atorvastatin impurities
• 
• Impurity: Atorvastatin pyrrolidone analog
• Chemical Name: (3R,5R)-7-[5-(4-Fluorophenyl)-2,3-dihydro-3-(1-methylethyl)-2-oxo-4-phenyl-3-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]-3,5-dihydroxy-heptanoic acid sodium salt

• Atorvastatin impurities
• 
• Impurity: Atorvastatin Cyclic Isopropyl Impurity or Atorvastatin Epoxy Pyrrol
• Chemical Name: 4-{6-(4-Fluorophenyl)-7,8-epoxy-6-hydroxy-8a-isopropyl7phenyl8(phenylcarbamoyl)hexahydro-2H -pyrrolo[2,1-b][1,3]oxazin-2-yl}-3-hydroxybutanoic acid sodium salt

• Atorvastatin Epoxy Pyrrolooxazin Tricyclic Analog
• 
• Impurity: Atorvastatin Impurity
• Chemical Name: 2,6-(2-Carboxymethyl-3-oxapropano)-7,8-epoxy-8a-(4-fluorophenyl)-6-isopropyl-N,8-diphenylhexahydro-2H -pyrrolo[2,1-b][1,3]oxazine-7-carboxamide

• Atorvastatin FX1 Impurity
• 
• Impurity: Atorvastatin Impurity
• Chemical Name: 1b-(4-Fluorophenyl)hexahydro-β,7-dihydroxy-7-(1-methylethyl)-1a-phenyl-7a-[(phenylamino)carbonyl]-3H-oxireno[3,4]pyrrolo[2,1-b][1,3]oxazine-3-butanoic acid sodium salt

• Atorvastatin Cyclic Fluorophenyl Impurity
• 
• Impurity: Atorvastatin Impurity
• Chemical Name: 1b-(4-Fluorophenyl)hexahydro-β,7-dihydroxy-7-(1-methylethyl)-1a-phenyl-7a-[(phenylamino)carbonyl]-3H-oxireno[3,4]pyrrolo[2,1-b][1,3]oxazine-3-butanoic acid sodium salt

• Atorvastatin Cyclic 7-Hydroxy Impurity
• 
• Impurity: Atorvastatin Impurity
• Chemical Name: 1b-(4-Fluorophenyl)hexahydro-β,7-dihydroxy-7-(1-methylethyl)-1a-phenyl-7a-[(phenylamino)carbonyl]-3H-oxireno[3,4]pyrrolo[2,1-b][1,3]oxazine-3-butanoic acid sodium salt

• Atorvastatin Cyclic FP impurity
• 
• Impurity: Atorvastatin Impurity
• Chemical Name: 1b-(4-Fluorophenyl)hexahydro-β,7-dihydroxy-7-(1-methylethyl)-1a-phenyl-7a-[(phenylamino)carbonyl]-3H-oxireno[3,4]pyrrolo[2,1-b][1,3]oxazine-3-butanoic acid sodium salt

• Atorvastatin FXA Impurity
• 
• Impurity: Atorvastatin Impurity
• Chemical Name: 4-{6-(4-Fluorophenyl)-7,8-epoxy-6-hydroxy-8a-isopropyl-7-phenyl-8-(phenylcarbamoyl)hexahydro-2H -pyrrolo[2,1-b][1,3]oxazin-2-yl}-3-hydroxybutanoic acid sodium salt

• Atorvastatin Cyclic Isopropyl Impurity
• 
• Impurity: Atorvastatin Cyclic Isopropyl Impurity
• Chemical Name: 4-{6-(4-Fluorophenyl)-7,8-epoxy-6-hydroxy-8a-isopropyl-7-phenyl-8-(phenylcarbamoyl)hexahydro-2H -pyrrolo[2,1-b][1,3]oxazin-2-yl}-3-hydroxybutanoic acid sodium salt

• Atorvastatin Epoxy Pyrrolooxazin Analog
• 
• Impurity: Atorvastatin Epoxy Pyrrolooxazin Analog
• Chemical Name: 4-{6-(4-Fluorophenyl)-7,8-epoxy-6-hydroxy-8a-isopropyl-7-phenyl-8-(phenylcarbamoyl)hexahydro-2H -pyrrolo[2,1-b][1,3]oxazin-2-yl}-3-hydroxybutanoic acid sodium salt

• Atorvastatin Cyclic 6-Hydroxy Impurity
• 
• Impurity: Atorvastatin Cyclic 6-Hydroxy Impurity
• Chemical Name: 4-{6-(4-Fluorophenyl)-7,8-epoxy-6-hydroxy-8a-isopropyl-7-phenyl-8-(phenylcarbamoyl)hexahydro-2H -pyrrolo[2,1-b][1,3]oxazin-2-yl}-3-hydroxybutanoic acid sodium salt

• Atorvastatin Lactam
• 
• Impurity: Atorvastatin Lactam Impurity
• Chemical Name: (3R,5R)-7-[5-(4-Fluorophenyl)-2,3-dihydro-3-(1-methylethyl)-2-oxo-4-phenyl-3-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]-3,5-dihydroxy-heptanoic acid sodium salt

• Atorvastatin Pyrrolidone Analog
• 
• Impurity: Atorvastatin Pyrrolidone Analog impurity
• Chemical Name: (3R,5R)-7-[5-(4-Fluorophenyl)-2,3-dihydro-3-(1-methylethyl)-2-oxo-4-phenyl-3-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]-3,5-dihydroxy-heptanoic acid sodium salt

• Atorvastatin Epoxy Pyrrolooxazin Tricyclic Analog impurity
• 
• Impurity: Atorvastatin Epoxy Pyrrolooxazin Tricyclic Analog impurity
• Chemical Name: 2,6-(2-Carboxymethyl-3-oxapropano)-7,8-epoxy-8a-(4-fluorophenyl)-6-isopropyl-N,8-diphenylhexahydro-2H -pyrrolo[2,1-b][1,3]oxazine-7-carboxamide

• Atorvastatin Epoxy Tetrahydrofuran Analog
• 
• Impurity: Atorvastatin Epoxy Tetrahydrofuran Analog impurity
• Chemical Name: 4-(4-Fluorophenyl)-2,4-dihydroxy-2-isopropyl-N,5-diphenyl-3,6-dioxabicyclo [3.1.0]hexane-1-carboxamide

• Atorvastatin Dihydroxy Epoxy Impurity
• 
• Impurity: Atorvastatin Dihydroxy Epoxy Impurity
• Chemical Name: 4-(4-Fluorophenyl)-2,4-dihydroxy-2-isopropyl-N,5-diphenyl-3,6-dioxabicyclo [3.1.0]hexane-1-